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Hypoxic expression of NLRP3 and VEGF in cultured retinal pigment epithelial cells: contribution of P2Y(2) receptor signaling

Retinal hypoxia is a major condition of the chronic inflammatory disease age-related macular degeneration. Extracellular ATP is a danger signal which is known to activate the NLRP3 inflammasome in various cell systems. We investigated in cultured human retinal pigment epithelial (RPE) cells whether...

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Bibliografske podrobnosti
izdano v:Purinergic Signal
Main Authors: Doktor, Fabian, Prager, Philipp, Wiedemann, Peter, Kohen, Leon, Bringmann, Andreas, Hollborn, Margrit
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298930/
https://ncbi.nlm.nih.gov/pubmed/30415294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-018-9631-6
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