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Osmotic and hypoxic induction of osteopontin in retinal pigment epithelial cells: Involvement of purinergic receptor signaling

PURPOSE: Osteopontin (OPN) is a neuroprotective factor in the retina that improves photoreceptor survival. The aim of the present study was to investigate whether human RPE cells express and respond to OPN. METHODS: Hypoxia and chemical hypoxia were induced by cell culture in 0.25% O(2) and the addi...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Hollborn, Margrit, Brück, Ricarda, Kuhrt, Heidrun, Wiedemann, Peter, Bringmann, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086046/
https://ncbi.nlm.nih.gov/pubmed/32214785
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