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Administration of an antagonist of P2X7 receptor to EAE rats prevents a decrease of expression of claudin-5 in cerebral capillaries

Purinergic P2X receptors, when activated under pathological conditions, participate in induction of the inflammatory response and/or cell death. Both neuroinflammation and neurodegeneration represent hallmarks of multiple sclerosis (MS), an autoimmune disease of the central nervous system. In the cu...

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Detalles Bibliográficos
Publicado en:Purinergic Signal
Autores principales: Grygorowicz, Tomasz, Dąbrowska-Bouta, Beata, Strużyńska, Lidia
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Netherlands 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298928/
https://ncbi.nlm.nih.gov/pubmed/30091000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-018-9620-9
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