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Modulation of Neurological Deficits and Expression of Glutamate Receptors during Experimental Autoimmune Encephalomyelitis after Treatment with Selected Antagonists of Glutamate Receptors

The aim of our investigation was to characterize the role of group I mGluRs and NMDA receptors in pathomechanisms of experimental autoimmune encephalomyelitis (EAE), the rodent model of MS. We tested the effects of LY 367385 (S-2-methyl-4-carboxyphenylglycine, a competitive antagonist of mGluR1), MP...

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Détails bibliographiques
Auteurs principaux: Sulkowski, Grzegorz, Dąbrowska-Bouta, Beata, Strużyńska, Lidia
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722774/
https://ncbi.nlm.nih.gov/pubmed/23936777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/186068
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