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A Chymase Inhibitory RNA Aptamer Improves Cardiac Function and Survival after Myocardial Infarction
We have reported that mast cell chymase, an angiotensin II-generating enzyme, is important in cardiovascular tissues. Recently, we developed a new chymase-specific inhibitory RNA aptamer, HA28, and we evaluated the effects of HA28 on cardiac function and the mortality rate after myocardial infarctio...
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| Izdano u: | Mol Ther Nucleic Acids |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Gene & Cell Therapy
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6298900/ https://ncbi.nlm.nih.gov/pubmed/30572223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.11.001 |
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