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Genetic complexity in the replication-competent latent HIV reservoir increases with untreated infection duration in infected youth

OBJECTIVE: Timely initiation of combination antiretroviral therapy (ART) limits latent HIV reservoir size and should also limit reservoir genetic complexity. However, the relationship between these two factors remains unclear, particularly among HIV-infected youth. DESIGN: Retrospective analysis of...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: BRUMME, Zabrina L., SUDDERUDDIN, Hanwei, ZIEMNIAK, Carrie, LUZURIAGA, Katherine, JONES, Bradley R., JOY, Jeffrey B., CUNNINGHAM, Coleen K., GREENOUGH, Thomas, PERSAUD, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298800/
https://ncbi.nlm.nih.gov/pubmed/30325763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002045
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