TLR4 deficiency reduces pulmonary resistance to Streptococcus pneumoniae in gut microbiota-disrupted mice

Streptococcus pneumoniae is a clinically important pathogen responsible for significant morbidity and mortality worldwide. Disruption of the host gut microbiota by antibiotics reduces the pulmonary resistance to S. pneumoniae. The aim of our study was to determine the potential role of TLR4 in the r...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Wang, Hongyan, Lian, Pengjing, Niu, Xiaofei, Zhao, Lihong, Mu, Xiang, Feng, Bo, Li, Jingyun, Liang, Zhenni, Qiao, Jian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298678/
https://ncbi.nlm.nih.gov/pubmed/30562386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209183
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