Osteopontin Deficiency Accelerates Spontaneous Colitis in Mice with Disrupted Gut Microbiota and Macrophage Phagocytic Activity

BACKGROUND: Osteopontin (OPN) is a multifunctional protein expressed in a variety of tissues and cells. Recent studies revealed increased OPN expression in the inflamed intestinal tissues of patients with inflammatory bowel disease (IBD). The role of OPN in the pathophysiology of IBD, however, remai...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Toyonaga, Takahiko, Nakase, Hiroshi, Ueno, Satoru, Matsuura, Minoru, Yoshino, Takuya, Honzawa, Yusuke, Itou, Ayako, Namba, Kazuyoshi, Minami, Naoki, Yamada, Satoshi, Koshikawa, Yorimitsu, Uede, Toshimitsu, Chiba, Tsutomu, Okazaki, Kazuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537118/
https://ncbi.nlm.nih.gov/pubmed/26274807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135552
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados