Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography–Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults

BACKGROUND: Growth and differentiation factors 8 (GDF8) and 11 (GDF11) have attracted attention as targets for rejuvenating interventions. The biological activity of these proteins may be affected by circulating antagonists such as their respective prodomains, follistatin (FST315), WFIKKN1, and WFIK...

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Veröffentlicht in:J Gerontol A Biol Sci Med Sci
Hauptverfasser: Semba, Richard D, Zhang, Pingbo, Zhu, Min, Fabbri, Elisa, Gonzalez-Freire, Marta, Carlson, Olga D, Moaddel, Ruin, Tanaka, Toshiko, Egan, Josephine M, Ferrucci, Luigi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
The Journal of Gerontology: Medical Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298188/
https://ncbi.nlm.nih.gov/pubmed/30380014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly255
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