Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography–Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults

BACKGROUND: Growth and differentiation factors 8 (GDF8) and 11 (GDF11) have attracted attention as targets for rejuvenating interventions. The biological activity of these proteins may be affected by circulating antagonists such as their respective prodomains, follistatin (FST315), WFIKKN1, and WFIK...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Semba, Richard D, Zhang, Pingbo, Zhu, Min, Fabbri, Elisa, Gonzalez-Freire, Marta, Carlson, Olga D, Moaddel, Ruin, Tanaka, Toshiko, Egan, Josephine M, Ferrucci, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
The Journal of Gerontology: Medical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298188/
https://ncbi.nlm.nih.gov/pubmed/30380014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly255
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