Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Irisin is secreted by muscle, increased with exercise and mediates certain favorable effects of physical activity. In particular, irisin has been shown to have beneficial effects in adipose tissues, brain and bone. However, the skeletal response to exercise is less clear and the receptor for irisin...

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Published in:Cell
Main Authors: Kim, Hyeonwoo, Wrann, Christiane D., Jedrychowski, Mark, Vidoni, Sara, Kitase, Yukiko, Nagano, Kenichi, Zhou, Chenhe, Chou, Joshua, Parkman, Virginia-Jeni A., Novick, Scott J., Strutzenberg, Timothy S., Pascal, Bruce D., Le, Phuong T., Brooks, Daniel J., Roche, Alexander M., Gerber, Kaitlyn K., Mattheis, Laura, Chen, Wenjing, Tu, Hua, Bouxsein, Mary L., Griffin, Patrick R., Baron, Roland, Rosen, Clifford J., Bonewald, Lynda F., Spiegelman, Bruce M.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298040/
https://ncbi.nlm.nih.gov/pubmed/30550785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.10.025
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