Ig-Like Transcript 2 (ILT2) Blockade and Lenalidomide Restore NK Cell Function in Chronic Lymphocytic Leukemia

One of the cardinal features of chronic lymphocytic leukemia (CLL) is its association with a profound immunosuppression. NK cell function is markedly impaired in CLL patients, who show a significant dysregulation of the expression of activating and inhibitory receptors. Here, we analyzed the role of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Villa-Álvarez, Mónica, Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Gonzalez-Rodriguez, Ana P., Payer, Angel R., Gonzalez-Garcia, Esther, Villa-Álvarez, María C., López-Soto, Alejandro, Gonzalez, Segundo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297751/
https://ncbi.nlm.nih.gov/pubmed/30619281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02917
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