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Mechanisms of Apoptosis Resistance to NK Cell-Mediated Cytotoxicity in Cancer

Natural killer (NK) cells are major contributors to immunosurveillance and control of tumor development by inducing apoptosis of malignant cells. Among the main mechanisms involved in NK cell-mediated cytotoxicity, the death receptor pathway and the release of granules containing perforin/granzymes...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Payer, Ángel R., Gonzalez, Segundo, López-Soto, Alejandro
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279491/
https://ncbi.nlm.nih.gov/pubmed/32466293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103726
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