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Mechanisms of Apoptosis Resistance to NK Cell-Mediated Cytotoxicity in Cancer

Natural killer (NK) cells are major contributors to immunosurveillance and control of tumor development by inducing apoptosis of malignant cells. Among the main mechanisms involved in NK cell-mediated cytotoxicity, the death receptor pathway and the release of granules containing perforin/granzymes...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Payer, Ángel R., Gonzalez, Segundo, López-Soto, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279491/
https://ncbi.nlm.nih.gov/pubmed/32466293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103726
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