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cPLA(2)α(-/-) sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca(2+) current inhibition by M(1) muscarinic receptor signaling
Group IVa cytosolic phospholipase A(2) (cPLA(2)α) mediates GPCR-stimulated arachidonic acid (AA) release from phosphatidylinositol 4,5-bisphosphate (PIP(2)) located in plasma membranes. We previously found in superior cervical ganglion (SCG) neurons that PLA(2) activity is required for voltage-indep...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6296557/ https://ncbi.nlm.nih.gov/pubmed/30557348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201322 |
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