Immunosuppression of Syrian golden hamsters accelerates relapse but not the emergence of resistance in Leishmania infantum following recurrent miltefosine pressure

Although miltefosine (MIL) has only been approved for the treatment of visceral leishmaniasis (VL) in 2002, its application in monotherapy already led to the development of two confirmed MIL-resistant isolates by 2009. Although liposomal amphotericin B is recommended as first-line treatment in Europ...

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發表在:Int J Parasitol Drugs Drug Resist
Main Authors: Hendrickx, S., Bulté, D., Van den Kerkhof, M., Cos, P., Delputte, P., Maes, L., Caljon, G.
格式: Artigo
語言:Inglês
出版: Elsevier 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296292/
https://ncbi.nlm.nih.gov/pubmed/30562667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.12.001
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