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FORGe: prioritizing variants for graph genomes
There is growing interest in using genetic variants to augment the reference genome into a graph genome, with alternative sequences, to improve read alignment accuracy and reduce allelic bias. While adding a variant has the positive effect of removing an undesirable alignment score penalty, it also...
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| Publicado en: | Genome Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6296055/ https://ncbi.nlm.nih.gov/pubmed/30558649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1595-x |
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