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Boiler: lossy compression of RNA-seq alignments using coverage vectors
We describe Boiler, a new software tool for compressing and querying large collections of RNA-seq alignments. Boiler discards most per-read data, keeping only a genomic coverage vector plus a few empirical distributions summarizing the alignments. Since most per-read data is discarded, storage footp...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027496/ https://ncbi.nlm.nih.gov/pubmed/27298258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw540 |
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