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Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation

We describe herein a Pd-catalyzed methodology for the thioglycoconjugation of iodoaryl peptides and aminoacids. This operationally simple process occurs under semi-aqueous conditions and displays wide substrate scope. The strategy has been successfully applied to both the thioglycosylation of unprot...

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Publicado en:Chem Sci
Main Authors: Montoir, David, Amoura, Mehdi, Ababsa, Zine El Abidine, Vishwanatha, T. M., Yen-Pon, Expédite, Robert, Vincent, Beltramo, Massimiliano, Piller, Véronique, Alami, Mouad, Aucagne, Vincent, Messaoudi, Samir
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295873/
https://ncbi.nlm.nih.gov/pubmed/30627396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02370k
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