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Design, Synthesis, and Characterization of a Fluorescence Polarization Pan-BET Bromodomain Probe
[Image: see text] Several chemical probes have been developed for use in fluorescence polarization screening assays to aid in drug discovery for the bromodomain and extra-terminal domain (BET) proteins. However, few of those have been characterized in the literature. We have designed, synthesized, a...
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| Pubblicato in: | ACS Med Chem Lett |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2018
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295860/ https://ncbi.nlm.nih.gov/pubmed/30613330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00380 |
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