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Restoring Let-7 microRNA Biogenesis Using a Small-Molecule Inhibitor of the Protein–RNA Interaction
[Image: see text] Abnormal function of RNA-binding proteins can lead to dysregulation of RNA function, causing a variety of disease states. Thus, developing small-molecule modulators of protein–RNA interactions is one of the key challenges in chemical biology. Herein, we performed a high-throughput...
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| Yayımlandı: | ACS Med Chem Lett |
|---|---|
| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical
Society
2018
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295851/ https://ncbi.nlm.nih.gov/pubmed/30613323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00323 |
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