5-Diphosphoinositol pentakisphosphate (5-IP(7)) regulates phosphate release from acidocalcisomes and yeast vacuoles

Acidocalcisomes of Trypanosoma brucei and the acidocalcisome-like vacuoles of Saccharomyces cerevisiae are acidic calcium compartments that store polyphosphate (polyP). Both organelles possess a phosphate–sodium symporter (TbPho91 and Pho91p in T. brucei and yeast, respectively), but the roles of th...

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Foilsithe in:J Biol Chem
Main Authors: Potapenko, Evgeniy, Cordeiro, Ciro D., Huang, Guozhong, Storey, Melissa, Wittwer, Christopher, Dutta, Amit K., Jessen, Henning J., Starai, Vincent J., Docampo, Roberto
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Microbiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295732/
https://ncbi.nlm.nih.gov/pubmed/30315104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005884
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