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Prospects for gene-engineered T cell immunotherapy for solid cancers

Adoptive transfer of receptor-engineered T cells has produced impressive results in treating patients with B cell leukemias and lymphomas. This success has captured public imagination and driven academic and industrial researchers to develop similar ‘off-the-shelf’ receptors targeting shared antigen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Med
Hauptverfasser: Klebanoff, Christopher A, Rosenberg, Steven A, Restifo, Nicholas P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295670/
https://ncbi.nlm.nih.gov/pubmed/26735408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4015
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