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Curcumin Derivative Epigenetically Reactivates Nrf2 Antioxidative Stress Signaling in Mouse Prostate Cancer TRAMP C1 Cells

The carcinogenesis of prostate cancer (PCa) in TRAMP model is highly correlated with hypermethylation in the promoter region of Nrf2 and the accompanying reduced transcription of Nrf2 and its regulated detoxifying genes. We aimed to investigate the effects of (3E,5E)-3,5-Bis(3,4,5-trimethoxybenzylid...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chem Res Toxicol
Päätekijät: Li, Wenji, Su, Zheng-Yuan, Guo, Yue, Zhang, Chengyue, Wu, Renyi, Gao, Linbo, Zheng, Xi, Du, Zhi-Yun, Zhang, Kun, Kong, Ah-Ng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295337/
https://ncbi.nlm.nih.gov/pubmed/29228771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00248
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