The NCI Transcriptional Pharmacodynamics Workbench: a tool to examine dynamic expression profiling of therapeutic response in the NCI-60 cell line panel

The intracellular effects and overall efficacies of anticancer therapies can vary significantly by tumor type. To identify patterns of drug-induced gene modulation that occur in different cancer cell types, we measured gene expression changes across the NCI-60 cell line panel after exposure to 15 an...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Monks, Anne, Zhao, Yingdong, Hose, Curtis, Hamed, Hossein, Krushkal, Julia, Fang, Jianwen, Sonkin, Dmitriy, Palmisano, Alida, Polley, Eric C., Fogli, Laura K., Konaté, Mariam M., Miller, Sarah B., Simpson, Melanie A., Voth, Andrea Regier, Li, Ming-Chung, Harris, Erik, Wu, Xiaolin, Connelly, John W., Rapisarda, Annamaria, Teicher, Beverly A., Simon, Richard, Doroshow, James H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295263/
https://ncbi.nlm.nih.gov/pubmed/30355619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0989
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