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KMT2C mutations in diffuse type gastric adenocarcinoma promote epithelial-to-mesenchymal transition
PURPOSE: Lauren diffuse type gastric adenocarcinoma (DGA) is genomically stable. We identified lysine (K)-specific methyltransferase 2C (KMT2C) as a frequently mutated gene and examined its role in DGA progression. EXPERIMENTAL DESIGN AND RESULTS: Whole exome sequencing on tumor samples of 27 patien...
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| Publié dans: | Clin Cancer Res |
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| Auteurs principaux: | , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295255/ https://ncbi.nlm.nih.gov/pubmed/30108106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1679 |
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