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A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
We combine single-cell RNA-seq and in vivo lineage tracing to study the cellular composition and hierarchy of the murine tracheal epithelium. We identify a new rare cell type, the FoxI1-positive pulmonary ionocyte; functional variations in club cells based on their proximodistal location; a distinct...
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| Publicado no: | Nature |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6295155/ https://ncbi.nlm.nih.gov/pubmed/30069044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0393-7 |
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