Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence

Long noncoding RNAs (lncRNAs) function through a diverse array of mechanisms that are not presently fully understood. Here, we sought to find lncRNAs differentially regulated in cancer cells resistant to either TNF-related apoptosis-inducing ligand (TRAIL) or the Mcl-1 inhibitor UMI-77, agents that...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sang, Ben, Zhang, Yuan Yuan, Guo, Su Tang, Kong, Ling Fei, Cheng, Qiong, Liu, Guang Zhi, Thorne, Rick F., Zhang, Xu Dong, Jin, Lei, Wu, Mian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294934/
https://ncbi.nlm.nih.gov/pubmed/30478051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805950115
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