Carregant...

TRPV1 pore turret dictates distinct DkTx and capsaicin gating

Many neurotoxins inflict pain by targeting receptors expressed on nociceptors, such as the polymodal cationic channel TRPV1. The tarantula double-knot toxin (DkTx) is a peptide with an atypical bivalent structure, providing it with the unique capability to lock TRPV1 in its open state and evoke an i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Geron, Matan, Kumar, Rakesh, Zhou, Wenchang, Faraldo-Gómez, José D., Vásquez, Valeria, Priel, Avi
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294906/
https://ncbi.nlm.nih.gov/pubmed/30463948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809662115
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!