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Hippo signaling dysfunction induces cancer cell addiction to YAP

Over the past decades, the Hippo has been established as a crucial pathway involved in organ size control and cancer suppression. Dysregulation of Hippo signaling and hyperactivation of its downstream effector YAP are frequently associated with various human cancers. However, the underlying signific...

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Bibliografische gegevens
Gepubliceerd in:Oncogene
Hoofdauteurs: Han, Han, Yang, Bing, Nakaoka, Hiroki J, Yang, Jiadong, Zhao, Yifan, Le Nguyen, Kathern, Bishara, Amell Taffy, Mandalia, Tejas Krishen, Wang, Wenqi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294669/
https://ncbi.nlm.nih.gov/pubmed/30068939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0419-5
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