LOTUS Inhibits Neuronal Apoptosis and Promotes Tract Regeneration in Contusive Spinal Cord Injury Model Mice

Nogo receptor-1 (NgR1) signaling is involved in the limitation of axonal regeneration following spinal cord injury (SCI) through collapsing the growth cone and inhibiting neurite outgrowth. Lateral olfactory tract usher substance (LOTUS), a NgR antagonist, suppresses these pathological conditions. A...

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Publicado en:eNeuro
Autores principales: Ito, Shuhei, Nagoshi, Narihito, Tsuji, Osahiko, Shibata, Shinsuke, Shinozaki, Munehisa, Kawabata, Soya, Kojima, Kota, Yasutake, Kaori, Hirokawa, Tomoko, Matsumoto, Morio, Takei, Kohtaro, Nakamura, Masaya, Okano, Hideyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2018
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Confirmation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294604/
https://ncbi.nlm.nih.gov/pubmed/30560203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0303-18.2018
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