Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury

Treatment involving regenerative medicine for chronic spinal cord injury (SCI) is difficult due to phase-dependent changes in the intraspinal environment. We previously reported that treatment with a gamma-secretase inhibitor (GSI), which inhibits Notch signaling, promotes the differentiation into m...

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Publicado en:Stem Cell Reports
Main Authors: Okubo, Toshiki, Nagoshi, Narihito, Kohyama, Jun, Tsuji, Osahiko, Shinozaki, Munehisa, Shibata, Shinsuke, Kase, Yoshitaka, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294244/
https://ncbi.nlm.nih.gov/pubmed/30503258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.10.022
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