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Rhodium-catalyzed, P-directed selective C7 arylation of indoles

The indole scaffold will continue to play a vital role in the future of drug discovery and agrochemical development. Regioselective direct arylation of indoles on the benzenoid moiety is a challenging task due to the inherent reactivity of the C2 and C3 positions. Here, we have developed an effectiv...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Qiu, Xiaodong, Deng, Hong, Zhao, Yue, Shi, Zhuangzhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294599/
https://ncbi.nlm.nih.gov/pubmed/30555918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau6468
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