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Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome

R-loops are stable RNA–DNA hybrids that have been implicated in transcription initiation and termination, as well as in telomere maintenance, chromatin formation, and genome replication and instability. RNA Polymerase (Pol) II transcription in the protozoan parasite Trypanosoma brucei is highly unus...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Briggs, Emma, Hamilton, Graham, Crouch, Kathryn, Lapsley, Craig, McCulloch, Richard
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294496/
https://ncbi.nlm.nih.gov/pubmed/30304482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky928
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