Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop ‘G4 Kissing’ interaction

Mammalian antibody switch regions (∼1500 bp) are composed of a series of closely neighboring G4-capable sequences. Whereas numerous structural and genome-wide analyses of roles for minimal G4s in transcriptional regulation have been reported, Long G4-capable regions (LG4s)—like those at antibody swi...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Williams, Jonathan D, Houserova, Dominika, Johnson, Bradley R, Dyniewski, Brad, Berroyer, Alexandra, French, Hannah, Barchie, Addison A, Bilbrey, Dakota D, Demeis, Jeffrey D, Ghee, Kanesha R, Hughes, Alexandra G, Kreitz, Naden W, McInnis, Cameron H, Pudner, Susanna C, Reeves, Monica N, Stahly, Ashlyn N, Turcu, Ana, Watters, Brianna C, Daly, Grant T, Langley, Raymond J, Gillespie, Mark N, Prakash, Aishwarya, Larson, Erik D, Kasukurthi, Mohan V, Huang, Jingshan, Jinks-Robertson, Sue, Borchert, Glen M
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293029/
https://ncbi.nlm.nih.gov/pubmed/32383760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa357
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