Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM

Glioblastoma multiforme (GBM) remains a cancer with a poor prognosis and few effective therapeutic options. Successful medical management of GBM is limited by the restricted access of drugs to the central nervous system (CNS) caused by the blood brain barrier (BBB). We previously showed that a subse...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Przystal, Justyna Magdalena, Hajji, Nabil, Khozoie, Combiz, Renziehausen, Alexander, Zeng, Qingyu, Abaitua, Fernando, Hajitou, Amin, Suwan, Keittisak, Want, Elizabeth, Bomalaski, John, Szlosarek, Peter, O’Neill, Kevin, Crook, Tim, Syed, Nelofer
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294248/
https://ncbi.nlm.nih.gov/pubmed/30546006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1195-4
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