Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM

Glioblastoma multiforme (GBM) remains a cancer with a poor prognosis and few effective therapeutic options. Successful medical management of GBM is limited by the restricted access of drugs to the central nervous system (CNS) caused by the blood brain barrier (BBB). We previously showed that a subse...

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Vydáno v:Cell Death Dis
Hlavní autoři: Przystal, Justyna Magdalena, Hajji, Nabil, Khozoie, Combiz, Renziehausen, Alexander, Zeng, Qingyu, Abaitua, Fernando, Hajitou, Amin, Suwan, Keittisak, Want, Elizabeth, Bomalaski, John, Szlosarek, Peter, O’Neill, Kevin, Crook, Tim, Syed, Nelofer
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294248/
https://ncbi.nlm.nih.gov/pubmed/30546006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1195-4
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