The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays

Predicting developmental potency and risk of posttransplantation tumor formation by human pluripotent stem cells (hPSCs) and their derivatives largely rely on classical histological analysis of teratomas. Here, we investigated whether an assay based on microRNAs (miRNA) in blood plasma is able to de...

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Pubblicato in:Stem Cell Reports
Autori principali: Salvatori, Daniela C.F., Dorssers, Lambert C.J., Gillis, Ad J.M., Perretta, Gemma, van Agthoven, Ton, Gomes Fernandes, Maria, Stoop, Hans, Prins, Jan-Bas, Oosterhuis, J. Wolter, Mummery, Christine, Looijenga, Leendert H.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294243/
https://ncbi.nlm.nih.gov/pubmed/30503260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.11.002
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