Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation

The liver possesses a high regenerative capacity. Liver regeneration is a compensatory response overcoming disturbances of whole-body homeostasis provoked by organ defects. Here we show that a vagus-macrophage-hepatocyte link regulates acute liver regeneration after liver injury and that this system...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Izumi, Tomohito, Imai, Junta, Yamamoto, Junpei, Kawana, Yohei, Endo, Akira, Sugawara, Hiroto, Kohata, Masato, Asai, Yoichiro, Takahashi, Kei, Kodama, Shinjiro, Kaneko, Keizo, Gao, Junhong, Uno, Kenji, Sawada, Shojiro, Kalinichenko, Vladimir V., Ishigaki, Yasushi, Yamada, Tetsuya, Katagiri, Hideki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294142/
https://ncbi.nlm.nih.gov/pubmed/30546054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07747-0
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