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Genome Toxicity and Impaired Stem Cell Function after Conditional Activation of CreER(T2) in the Intestine
With the tamoxifen-inducible CreER(T2) system, genetic recombination can be temporally controlled in a cell-type-specific manner in intact animals, permitting dissection of the molecular underpinnings of mammalian physiology. Here we present a significant drawback to CreER(T2) technology for analysi...
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| Vydáno v: | Stem Cell Reports |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294112/ https://ncbi.nlm.nih.gov/pubmed/30449703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.10.014 |
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