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Personal Mutanomes Meet Modern Oncology Drug Discovery and Precision Health

Recent remarkable advances in genome sequencing have enabled detailed maps of identified and interpreted genomic variation, dubbed “mutanomes.” The availability of thousands of exome/genome sequencing data has prompted the emergence of new challenges in the identification of novel druggable targets...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmacol Rev
Hauptverfasser: Cheng, Feixiong, Liang, Han, Butte, Atul J., Eng, Charis, Nussinov, Ruth
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6294046/
https://ncbi.nlm.nih.gov/pubmed/30545954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.118.016253
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