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Kinesin-2 and IFT-A act as a complex promoting nuclear localization of β-catenin during Wnt signalling
Wnt/Wg-signalling is critical signalling in all metazoans. Recent studies suggest that IFT-A proteins and Kinesin-2 modulate canonical Wnt/Wg-signalling independently of their ciliary role. Whether they function together in Wnt-signalling and their mechanistic role in the pathway remained unresolved...
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| Veröffentlicht in: | Nat Commun |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294004/ https://ncbi.nlm.nih.gov/pubmed/30546012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07605-z |
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