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Absence of leptin signaling allows fat accretion in cystic fibrosis mice

Negative energy balance is a prevalent feature of cystic fibrosis (CF). Pancreatic insufficiency, elevated energy expenditure, lung disease, and malnutrition, all characteristic of CF, contribute to the negative energy balance causing low body-growth phenotype. As low body weight and body mass index...

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Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Bederman, Ilya R., Pora, Gavriella, O’Reilly, Maureen, Poleman, James, Spoonhower, Kimberly, Puchowicz, Michelle, Perez, Aura, Erokwu, Bernadette O., Rodriguez-Palacios, Alex, Flask, Chris A., Drumm, Mitchell L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293256/
https://ncbi.nlm.nih.gov/pubmed/30118352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00344.2017
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