Impairments in the reproductive axis of female mice lacking estrogen receptor β in GnRH neurons

The effect of estrogen on the differentiation and maintenance of reproductive tissues is mediated by two nuclear estrogen receptors (ERs), ERα, and ERβ. Lack of functional ERα and ERβ genes in vivo significantly affects reproductive function; however, the target tissues and signaling pathways in the...

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Veröffentlicht in:Am J Physiol Endocrinol Metab
Hauptverfasser: Novaira, Horacio J., Negron, Ariel L., Graceli, Jones B., Capellino, Silvia, Schoeffield, Andrew, Hoffman, Gloria E., Levine, Jon E., Wolfe, Andrew, Wondisford, Fredric E., Radovick, Sally
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6293171/
https://ncbi.nlm.nih.gov/pubmed/30040478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00173.2018
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