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The short-sequence design of DNA and its involvement in the 3-D structure of the genome

Recent investigations have shown that isochores are characterized by a 3-D structure which is primarily responsible for the topology of chromatin domains. More precisely, an analysis of human chromosome 21 demonstrated that low-heterogeneity, GC-poor isochores are characterized by the presence of ol...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lamolle, Guillermo, Sabbia, Victor, Musto, Héctor, Bernardi, Giorgio
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292894/
https://ncbi.nlm.nih.gov/pubmed/30546029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35864-9
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