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Presynaptic loss of dynamin‐related protein 1 impairs synaptic vesicle release and recycling at the mouse calyx of Held

KEY POINTS: This study characterizes the mechanisms underlying defects in synaptic transmission when dynamin‐related protein 1 (DRP1) is genetically eliminated. Viral‐mediated knockout of DRP1 from the presynaptic terminal at the mouse calyx of Held increased initial release probability, reduced the...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Singh, Mahendra, Denny, Henry, Smith, Christina, Granados, Jorge, Renden, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292820/
https://ncbi.nlm.nih.gov/pubmed/30285293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276424
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