TBX18 overexpression enhances pacemaker function in a rat subsidiary atrial pacemaker model of sick sinus syndrome

KEY POINTS: The sinoatrial node (SAN) is the primary pacemaker of the heart. SAN dysfunction, or ‘sick sinus syndrome’, can cause excessively slow heart rates and pauses, leading to exercise limitation and syncope, currently treated by implantation of an electronic pacemaker. ‘Biopacemaking’ utilise...

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發表在:J Physiol
Main Authors: Choudhury, M., Black, N., Alghamdi, A., D'Souza, A., Wang, R., Yanni, J., Dobrzynski, H., Kingston, P. A., Zhang, H., Boyett, M. R., Morris, G. M.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
主題:
Cardiovascular
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292813/
https://ncbi.nlm.nih.gov/pubmed/30259525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276508
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