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Hydroxynorketamine: Implications for the NMDA Receptor Hypothesis of Ketamine’s Antidepressant Action

The prevailing hypothesis of ketamine’s unique antidepressant effects implicates N-methyl-d-aspartate receptor (NMDAR) inhibition-dependent enhancement of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated transmission, activation of intracellular signalling pathways and increase...

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Détails bibliographiques
Publié dans:Chronic Stress (Thousand Oaks)
Auteurs principaux: Aleksandrova, Lily R., Wang, Yu Tian, Phillips, Anthony G.
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292673/
https://ncbi.nlm.nih.gov/pubmed/30556028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2470547017743511
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