Organic barn dust inhibits surfactant protein D production through protein kinase-c alpha dependent increase of GPR116

Prolonged exposure to organic barn dusts can lead to chronic inflammation and a broad range of lung problems over time, mediated by innate immune mechanisms. The immune surfactant or collectin surfactant protein D (SP-D) is a crucial multifunctional innate immune receptor. Little work to date has ex...

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Vydáno v:PLoS One
Hlavní autoři: Schneberger, David, DeVasure, Jane M., Kirychuk, Shelley A., Wyatt, Todd A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292596/
https://ncbi.nlm.nih.gov/pubmed/30543664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208597
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