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Pharmacological, Physiochemical, and Drug-Relevant Biological Properties of Short Chain Fatty Acid Hexosamine Analogs used in Metabolic Glycoengineering

In this study, we catalog structure activity relationships (SAR) of several short chain fatty acid (SCFA)-modified hexosamine analogs used in metabolic glycoengineering (MGE) by comparing in silico and experimental measurements of physiochemical properties important in drug design including of. We t...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Saeui, Christopher T., Liu, Lingshu, Urias, Esteban, Morrissette-McAlmon, Justin, Bhattacharya, Rahul, Yarema, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292510/
https://ncbi.nlm.nih.gov/pubmed/28853901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00525
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