Glycoengineering of Esterase Activity Through Metabolic Flux-Based Modulation of Sialic Acid

This report describes the metabolic glycoengineering (MGE) of intracellular esterase activity in human colon cancer (LS174T) and Chinese hamster ovary (CHO) cells. In silico analysis of the carboxylesterases CES1 and CES2 suggested that these enzymes are modified with sialylated N-glycans, which are...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Mathew, Mohit P., Tan, Elaine, Labonte, Jason W., Shah, Shivam, Saeui, Christopher T., Liu, Lingshu, Bhattacharya, Rahul, Bovonratwet, Patawut, Gray, Jeffrey J., Yarema, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757160/
https://ncbi.nlm.nih.gov/pubmed/28218815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600698
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