“Omics” data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy

BACKGROUND: Large-scale “omics” datasets have not been leveraged and integrated with functional analyses to discover potential drivers of cardiomyopathy. This study addresses the knowledge gap. METHODS: We coupled RNA sequence (RNA-Seq) variant detection and transcriptome profiling with pathway anal...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Campbell, Nzali V., Weitzenkamp, David A., Campbell, Ian L., Schmidt, Ronald F., Hicks, Chindo, Morgan, Michael J., Irwin, David C., Tentler, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292014/
https://ncbi.nlm.nih.gov/pubmed/30541556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0439-6
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