“Omics” data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy

BACKGROUND: Large-scale “omics” datasets have not been leveraged and integrated with functional analyses to discover potential drivers of cardiomyopathy. This study addresses the knowledge gap. METHODS: We coupled RNA sequence (RNA-Seq) variant detection and transcriptome profiling with pathway anal...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Med Genomics
Main Authors: Campbell, Nzali V., Weitzenkamp, David A., Campbell, Ian L., Schmidt, Ronald F., Hicks, Chindo, Morgan, Michael J., Irwin, David C., Tentler, John J.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292014/
https://ncbi.nlm.nih.gov/pubmed/30541556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-018-0439-6
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki